Set a target of 288 runs to win, Australia collapsed to 111 all out. Spinner Simon Harmer was the chief destroyer, returning career-best figures of 6-16, while Kagiso Rabada claimed 3-39, including the milestone 350th Test wicket of his career.

The defeat prompted sharp criticism from former Australian opener David Warner, who described the team's performance as "un-Australian" and "disgraceful." Warner highlighted the lack of fight shown by the visitors during their final-day pursuit of the target.

Australia's chase began disastrously in the first over of the day. Kagiso Rabada removed Matt Renshaw and Marnus Labuschagne in quick succession, leaving the tourists reeling. Travis Head also fell to Rabada, further compounding the pressure on the middle order.

The situation worsened when Josh Inglis was run out following a mix-up with Cameron Green. Harmer then exploited the conditions, dismissing Alex Carey and Cooper Connolly to leave Australia at 60-7 by the lunch interval, effectively ending their hopes of victory.

Following the break, Australia adopted a defensive approach, with captain Pat Cummins facing 40 deliveries before scoring a run. However, the resistance was short-lived as Harmer continued to weave his web, eventually claiming the final wicket to seal the win.

South Africa's victory was built on the foundation of centuries from Ryan Rickelton and Wiaan Mulder, who batted throughout the fourth day to set up the challenging target. Their efforts ensured the Proteas regained the top spot in the world Test rankings.

The result marks a significant setback for Pat Cummins' side, who now face a challenging schedule. Australia are set to host New Zealand for a four-Test series starting in December, followed by a five-Test tour of India.

The series loss raises questions regarding the composition of the Australian batting order, particularly following the struggles of Marnus Labuschagne, who has now gone 49 innings without a century. The team will look to regroup before the New Zealand series.

Brief scores: South Africa 329 & 387 (Wiaan Mulder 115, Ryan Rickelton 101) beat Australia 429 & 111 (Nathan Lyon 33*; Simon Harmer 6-16, Kagiso Rabada 3-39) by 176 runs.